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The following papers are closely related to the activities of Colibri Photonics and reflect our interest in science and research.


alt    CP_research   oxygen_pepper


C. Gehre; M. Flechner; S. Kammerer et al.
Real time monitoring of oxygen uptake of hepatocytes in a microreactor using optical microsensors
Scientific Reports 10, 13700 (2020). DOWNLOAD | Sci Rep.

A. Ehrlich; S. Tsytkin-Kirschenzweig; K. Ioannidis et al.
Microphysiological flux balance platform unravels the dynamics of drug induced steatosis
Lab on a Chip, Vol. 18, Issue 17 (2018). Lab Chip

T. Steege; M. Busek; S. Grünzner et al.
Closed-loop control system for well-definded oxygen supply in micro-physiological systems
Current Directions in Biomedical Engineering, Vol. 3, Issue 2 (September 7, 2017). DOWNLOAD | De Gruyter

M. Busek, S. Grünzner, T. Steege et al.
Current Directions in Biomedical Engineering, Vol. 2, Issue 1 (September 30, 2016). DOWNLOAD | De Gruyter 

F. Sonntag ; F. Schmieder ; J. Ströbel et al.
Universal lab-on-a-chip platform for complex, perfused 3D cell cultures
Proc. SPIE 9705, Microfluidics, BioMEMS, and Medical Microsystems XIV, 970516 (March 21, 2016). SPIE Digital Library

D. Bavli, S. Prill, Elishai E. et al.
Real-time monitoring of metabolic funtion in liver-on-chip microdevices tracks the dynamics of mitochondrial dysfucntion
PNAS Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 16, E2231 - E2240 (March 7th, 2016). PNAS

S. Prill, D. Bavli, E. Ezra et al.
Real-time monitoring of oxygen uptake in hepatic bioreactor shows CYP450-independent mitochondrial toxicity of 
acetaminophen and amiodarone 
Archives of Toxicology (June 2015). Archive of Toxicology Webpage

B. Weyand, M. Nöhre, E. Schmälzlin et al.
Noninvasive Oxygen Monitoring in Three-Dimensional Tissue Cultures Under Static and Dynamic Conditions
BioResearch Open Access Vol. 4.1 (2015), 266-277. DOWNLOAD | BioResearch Open Access Webpage

E. Schmälzlin, E. Horn, R. Zantl
Spatially-resolved oxygen measurements in biological samples

E. Schmälzlin, E. Horn, R. Zantl
Ortsaufgelöste Sauerstoffmessungen in biologischen Proben
BioPhotonik 2/2014, 1-2 (2014), 34-37. DOWNLOAD | Biophotonik Webpage

S. Prill, A. Andersson, D. B. Papkovsky, E. Schmälzlin
Intracellular O2 Measurements

GIT Laboratory Journal Europe, 1-2 (2014), 28-29. DOWNLOAD

C. Ast, E. Schmälzlin, H.-G. Löhmannsröben, J.T. van Dongen;
Optical Oxygen Micro- and Nanosensors for Plant Applications;
Sensors 12 (2012) 7015-7032. LINK

D. Steinbrück, E. Schmälzlin, F. Peinemann, M. U. Kumke;
An Innovative Laser-Based Sensing Platform for Realtime Optical Monitoring of Oxygen;
Proceedings of the 14th Joint International IMEKO TC1 + TC7 + TC 13 Symposium (2011). DOWNLOAD

S. Eich, E. Schmälzlin, H.-G. Löhmannsröben; 
Distributed Fiber Optical Sensing of Molecular Oxygen with OTDR
Proc. SPIE 7726 (2010) 77260A.

A. Zabalza, J.T. van Dongen, A. Froehlich, S. Oliver, B. Faix, J.G. Kapuganti, E. Schmälzlin, M. Igal, L. Orcaray, M. Royuela, P. Geigenberger; 
Regulation of Respiration and Fermentation to Control the Plant Internal Oxygen Concentration
Plant Physiology 149 (2009) 1087-1098.

S.N. Oliver, J.E. Lunn, E. Urbanczyk-Wochniak, A. Lytovchenko, J.T. van Dongen, B. Faix, E. Schmälzlin, A.R. Fernie, P. Geigenberger; 
Decreased Expression of Cytosolic Pyruvate Kinase in Potato Tubers Leads to a Decline in Pyruvate Resulting in an in Vivo Repression of the Alternative Oxidase
Plant Physiology 148 (2008) 1640-1654.

B. Schewe, E. Schmälzlin, B. Walz; 
Intracellular pH homeostasis and serotonin-induced pH changes in Calliphora salivary glands: the contribution of V-ATPase and carbonic anhydrase;
J. Exp. Biol. 211 (2008) 805-815. 

H.-G. Löhmannsröben, E. Schmälzlin; 
Minimally invasive fiber probes for optical in-vivo oxygen measurements with integrated optical thermometer;
Proc. SPIE 6770 (2007) 67700V.

C. Oesterhelt, E. Schmälzlin, J. M. Schmitt, H. Lokstein; 
Regulation of photosynthesis in the unicellular acidophilic red alga Galdieria sulphuraria;
Plant Journal 51 (2007) 500-511.

E. Schmälzlin, B. Walz, I. Klimant, B. Schewe, H.-G. Löhmannsröben; 
Monitoring hormone-induced oxygen consumption in the salivary glands of the blowfly, Calliphora vicina, by use of luminescent microbeads;
Sens. Actuators B, Chem. 119 (2006) 251-254.

H.-G. Löhmannsröben, M. Beck, N. Hildebrandt, E. Schmälzlin, J. T. van Dongen; 
New challenges in biophotonics: laser-based fluoroimmuno analysis and in vivo optical oxygen monitoring;
Proc. SPIE 6157 (2005) 61570E.

E. Schmälzlin, J. van Dongen, I. Klimant, B. Marmodée, M. Steup, J. Fisahn, P. Geigenberger, H.-G. Löhmannsröben; 
An optical multi-frequency phase modulation method using micro-beads for measuring intracellular oxygen concentrations in plants
Biophys. J. 89 (2005) 1339-1345.